But what is his work all about? Mateus investigated the role of proteins in Escherichia coli, a bacterium most commonly responsible for infections of the gastrointestinal tract. He analyzed the impact of removing over 100 proteins (one at a time) from this organism for his research titled, “The functional proteome landscape of Escherichia coli”.
Due to the increase in antibiotic resistance, Mateus used a new technology to study proteins of unknown function. The “thermal proteome profiling” methodology is based on the principle that essential protein interactions influence protein stability. Mateus used the methodology to discover which proteins interact with each other, which influence each other, and which have no contact. Both the data pool and methodology are now also available to other scientists.
“I was delighted when my supervisor told me that I had won the Karl Freudenberg Prize. It was a tremendous honor,” says Dr. Anggara. And what of his dreams for the future? Dr. Anggara is eager to continue working as a professor and making new scientific discoveries in his favorite country, Canada. Dr Mateus also wants to continue his career in science and continue making new discoveries. Enthusiasm for science and research, international experience and the goal of making new discoveries - that's what unites the two young scientists.